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Model-Based Clustering and Gene Selection via Bayesian Hierarchical Hidden Markov Models
I will present a Bayesian hierarchical model that simultaneously performs clustering and feature selection. The model is combined with hidden Markov processes with three states for modeling functional dependence between features. The three states of the hidden Markov process allow us to obtain biologically meaningful clusters and to better discriminate them. Both simulation studies and gene expression analysis in a kidney cancer study illustrate the reliability and success of this method. We used Gene Ontology to define functional similarities between genes.
Date and Time
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Additional Authors and Speakers (not including you)
Himadri Mukherjee
University of Minnesota Duluth
Language of Oral Presentation
English
Language of Visual Aids
English

Speaker

Edit Name Primary Affiliation
Thierry Chekouo University of Minnesota