Causal Inference on Missing Exposure via Robust Estimation

How to deal with missing data in observational studies is a common concern for causal inference. When the covariates are missing at random (MAR), multiple approaches have been provided to help solve the issue. However, if the exposure is MAR, few approaches are available and careful adjustments on both missingness and confounding issues are required. In this article, a new inverse probability weighting (IPW) estimator based on weighted estimating equations (WEE) is proposed to incorporate weights from both the missingness and PS models, which can reduce the joint effect of extreme weights in finite samples. Additionally, we develop a triple robust (TR) estimator via WEE to further protect against the misspecification of the model. Based on the simulation studies, WEE also outperform others approaches in terms of bias and standard error. Finally, an application study is conducted to identify the causal effect of the presence of cardiovascular disease on mortality for COVID-19 patients.

Date and Time: 

Monday, June 3, 2024 - 15:45 to 16:00

Additional Authors and Speakers: 

Yeying Zhu
University of Waterloo
Joel A. Dubin
University of Waterloo

Language of Oral Presentation: 

English / Anglais

Language of Visual Aids: 

English / Anglais

Type of Presentation: 

Oral Presentation

Session: 

Speaker

First Name Middle Name Last Name Primary Affiliation
Yuliang Shi University of Waterloo