The Department of Statistics and Actuarial Science at the University of Waterloo is pleased to announce that it is hosting a virtual conference entitled Biostatistics: Foundations and the Era of Data Science from April 28–April 29, 2022. This conference will feature talks by leading statistical scientists addressing current challenges in health research. Many of the analytical and inferential issues arise from the need to fit models for complex processes using large administrative data sources. Time will be devoted to discussing challenges, opportunities, and areas warranting further methodological development.